The Scripps Research Institute
PDB Molecule of the Month
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Our major goals are to understand the interaction and neutralization of foreign antigens by the immune system through structural studies
Broadly neutralizing antibodies targeting hemagglutinin stem revitalized hopes of a universal flu vaccine.
The first atomic-level structure of the HIV envelope trimer — long considered one of the most difficult targets in structural biology.
Crystal structure of an antigenically near-native, cleaved, stabilized, soluble HIV-1 Env trimer
VH1-69 antibodies that broadly neutralize almost all influenza A group 1 viruses constituted a breakthrough in the influenza field
The x-ray and electron microscopy structures differ markedly from predictions and provide valuable information for HCV drug and vaccine design
The Ultimate Decoy: Scientist Find Unique Protein That Misdirects Immune System
Integrative approaches using data from a wide variety of methods are yielding model structures of complex biological assemblies.
Characterization of Foreign Antigens Recognition by the Immune System.
Facilities & Resources
Hight Throughput / Integrative Structural Biology and Biophysical Facilities & Resources
News & Highlights
Progress Towards the Neutralization of Viral Pathogens such as FLU and HIV-1